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ROLE OF TRIFALA GUGGULU IN HYPERLIPIDAEMIA

by: shriram Published on30-09-13 09:49 PM
Hyperlipidaemia is a disease of modern era and is much more prevalent in highly sophisticated, modernized and western world. The most important reason may be the availability of all comforts for living to the homosapiens.

There is no direct reference of a single disease entity that can be directly correlated with the hyperlipidaemia. Moreover different scholars have different opinions about the nearest possible disease. Most of them have considered hyperlipidaemia under the heading of Medoroga or Medodosh. Few of them have considered as Rasagata-Snehavriddhi, Raktagata-Snehavriddhi or Rasa Raktagata- Snehavriddhi, whereas some are the suggesting considering hyperlipidaemia under the broad umbrella of Ama.

Considering above problems trial of safe, effective as well as cost effective and well tolerated pharmacological agent would greatly expand therapeutic armamentarium available to the physician to treat the 'hyperlipidaemias'.

AIM
1) To study the role of Trifala Guggulu in Hyperlipidaemia.
2) To study the etiopathogenesis of hyperlipidaemia according to Ayurveda and modern science.

OBJECTIVES
To assess the effect of the treatment on the various criteria of patient assessment -

  • WEIGHT

  • BMI

  • SERUM CHOLESTEROL

  • SERUM TRIGLISERIDES

  • SERUM LDL

  • SERUM HDL

  • SERUM VLDL



The concept of Meda and lipids:


























Meda Lipids
Ingestion of excessive Sneha (Ghrita,taila, Vasa & Majja)19
Intake of high fat diet (ghee, oils, marrow, butter etc.) increases body lipids.
Dietary intake of excessive Madhura Dravyas causes Medoroga20
Increased consumption of carbohydrates (especially sucrose enhances cholesterol level)23
Medo-Snigdhangata21 Fat gives an oily appearance to the body.
Meda is the main factor which is affected (Dushya) in Sthaulya and Prameha22
Obesity and diabetes are often associated with abnormal lipid levels.


The etiological factors described by Acharya, can be categorized under four groups i.e.
1. Dosha Dushtikara - Guru, Madhura, Sheeta Guna dominant diet.
2. Dhatu Daurbalyakar/ Khavaigunyakara-Avyayama, Avyavaya, Achintana, Nityaharsha etc.
3. Agnimandyakara - Ati Bhojana, Madhura, Snigdha pradhan Bhojana.
4. Beejadosha - It impairs Medodhatvagni Poshakansha, which ultimately provides base to Sanchaya of Ama in Medo Dhatu
leads to Medoroga.
Chikitsa comprehends following measures in Ayurveda viz:

- Preventive or prophylactic therapy
- Curative therapy

1. Nidana Parivarjana
2. Samshodhana
3. Samshamana 1) DOSE AND TIME
TRIFALA GUGGULU VATI - 1 gm. At VYANODAN KALA. i.e. 1 gm. Twice a day after meals
ANUPANA – KOSHNA JALA. DURATION OF TREATMENT: 3 months

HETU ABHYAS (STUDY OF ETIOLOGICAL FACTORS)










































































HETU NO.OF SUBJECTS HETU NO.OF SUBJECTS
AMADOSHA 25 ATIBHOJAN 06
ATI DRAVA AHAR 25 AHITBHOJAN 16
AKALIBHOJAN 20 JATHARAGNI VIKRUTI 28
ATI GURU AHAR 28 ATI SHIT AHAR 07
ATI SNIGDHA AHAR 22 CHINTA 27
ABHISHYANDI AHAR 21 BHAYA 13
AVYAYAM 20 VIRUDDHAHAR 13
AJIRNASHANA 31 ADHYASHANA 32
AGNIMANDYA 24 USHAHPAN 20
DIVASWAP 08 BHOJANOTTAR JALAPAN 23

















Observations S.Cholesterol day 0 S.Cholesterol day 90
Mean Value 212.38 173.66
Mean Difference -- 38.72
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