A Case of Secondar Hypertension


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Case Report

  • 50 yrs old lady was referred for e/o uncontrolled hypertension of ~ 1yr.
  • She had exertional dyspnoea & palpitations 1 yr ago & was detected to be having HTN .
  • Treated with Atenolol & Amlodipine- still BP was not control.
  • At referral she was asymptomatic & leading normal life.
  • No h/o edema, haematuria, PIH.
  • Mother,maternal uncle, sister & 2brothers had HTN.
O/E

  • Moderately built, apparently healthy middle aged lady. PR-86/min, regular,all PP+ with N.volume.
  • BP-170/100mmHg (both UL) -186 mmHg SBP (both LL).
  • No PICCLE & JVP.
  • Cardiac apex could not be localized.
  • S1 n, A2 loud, S4+, 3/6 ESM @ LSB+
  • Chest was clear with NVBS.
  • No FND & optic fundui- normal.
Abdomen

  • Normal shape & non tender.
  • Irregular,lobulated, non-tender, firm mass of ~12 cms was bimanually palpable in right lumbar area & was ballotable.
  • Liver & Spleen were non palpable.
  • Band of resonance was + over the mass.
  • No shifting dullness
  • Normal bowel sounds + . No Bruits.
  • 50 yr old lady
  • F H/o HTN
  • ? Secondary / primary HTN
  • Uncontrolled HTN (stage III, No TOD)
  • Palpable enlarged Rt kidney.
    • ADPKD, Hydronephrosis, solitary cyst, hypernephroma, renal tumors, Pheo.., Adrenal mass…
  • Suspect secondary HTN if
    • Onset is 50yrs.
    • Difficult to control(refractory) HTN.
    • Previously controlled HTN getting uncontrolled.
    • TOD @ detection of HTN
  • Causes of secondary HTN
    • Renal
      • AGN, Renal failure, ADPKD, RAS.
    • Endocrine
      • Cushing’s, Pheo, thyrotoxicosis, Conn`s syndrome, Acromegaly…
    • Drugs
      • NSAID, Steroids, OCP…
    • COA
    • PIH
    • Alcohol
    • Inv: Hb-11 g%, ESR 40 @ 1Hr.
    • Urine Alb +, 4-5 RBC/HPF, no casts.
    • B urea26 mg%, creat 1.2 mg%, RBS 97 mg%, s Na136meql, S K 3.8 meqL
    • ECG – LVH & CXR wnl.
    • Usg: B/L nephromegaly (16 & 14 cm.) with numerous thin walled anechoic cysts of 5-30mm size. No calculi, hydro nephrosis.
3 cysts were seen in the rt lobe of liver.

  • sug of ADPKD.
  • ADPKD, Secondary HTN, with LVH.
  • HTN controlled with Enalapril, Amlodipine & Methyl dopa.

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